Topera 3D Mapping SystemAbbott intends to solve one of the most critical and unmet needs in cardiac ablation for atrial fibrillation: better patient outcomes. For the first time, physicians can identify patient-specific sources that sustain serious heart rhythm disorders using the Topera® 3D Physiologic Rotor Mapping Solution.

The Topera 3D Physiologic Rotor Mapping Solution provides physicians a diagnostic tool that, for the first time, identifies and locates the unique patient-specific sources, which are believed to be an important sustaining mechanism of cardiac arrhythmias.

Studies that included the identification of rotors as part of the treatment planning have been associated with excellent long-term results with a single-procedure.1-5 With the ability to visualize individual rotors, the physician is able to tailor patient-specific treatment approaches, as opposed to the “one size fits all” traditional technique.

By being able to identify specific areas of electrical rotational activity, studies utilizing the Abbott Electrophysiology technology have demonstrated a long-term success rate, even in patients who are normally difficult to treat with the traditional procedure.1-8

With the ability to diagnose the mechanisms of complex cardiac arrhythmias, the Topera 3D Physiologic Rotor Mapping Solution enables individualized treatment approaches for each patient. By focusing on the precise sources that sustain arrhythmias, Abbott is turning the potential for single treatment freedom from atrial fibrillation (AF or Afib) into reality.

Abbott’s Topera 3D Physiologic Rotor Mapping Solution includes the FDA-cleared and CE-marked FIRMap® panoramic contact mapping tool and RhythmView® Workstation, which are used in combination to identify and localize the sustaining mechanisms of even the most complex and chaotic cardiac arrhythmias.

FIRMap

Designed with complex arrhythmias and associated heart anatomy in mind, the FIRMap (Focal Impulse and Rotor Modulation) panoramic contact-mapping tool optimizes the clinician’s view of full-chamber, continuous electrical activity. This unique diagnostic catheter is sized to the patient’s chamber, mapping the anatomy from a stable position. Data from the FIRMap catheter is sent to the RhythmView mapping system for processing.

RHYTHMView

The RhythmView Workstation provides a graphical display of the right and left atrial electrical activity to assist in the identification of rotors and focal impulses to facilitate patient-specific Afib treatment decisions.

  1. Arshad A, Mittal S, Musat D, et al. Long-Term Success From FIRM Ablation is Maintained Even if Acute Endpoint is Not Achieved. Heart Rhythm 2013; 10(P004-133).
  2. Baykaner T, Clopton P, Lalani GG et al. Targeted Ablation at Stable Atrial Fibrillation Sources Improves Success Over Conventional Ablation in High-Risk Patients: A Substudy of the CONFIRM Trial. Canadian J Cardiol 2013; 29:1218-1226.
  3. Miller JM, Krummen DE, Narayan SM et al. Multicenter Validation of Focal Impulse and Rotor Modulation (FIRM) Ablation for Atrial Fibrillation (CONFIRM- Multicenter Validation). AHA Scientific Sessions, Nov 2013; Oral presentation.
  4. Narayan SM, Krummen DE, Shivkumar K, Clopton P, Rappel W-J, Miller J. Treatment of atrial fibrillation by the ablation of localized sources: the conventional ablation for atrial fibrillation with or without focal impulse and rotor modulation: Confirm trial. J Am Coll Cardiol 2012; 60:628– 636.
  5. Narayan SM, Krummen DE, Clopton P, Shivkumar K, and Miller JM. Direct of Coincidental Elimination of Stable Rotors or Focal Sources May Explain Successful AF Ablation: On-Treatment Analysis of the CONFIRM Trial. J Am Coll Cardiol 2013;60(2):138-147.
  6. Chilukuri K, Dalal D, Gadrey S, et al. A prospective study evaluating the role of obesity and obstructive sleep apnea for outcomes after catheter ablation of atrial fibrillation. J Cardiovasc Electrophysiol. 2010;21(5):521–525.
  7. Hoyer FF, Lickett LM, Mittmann-Braun E, et al. High prevalence of obstructive sleep apnea in patients with resistant paroxysmal atrial fibrillation after pulmonary vein isolation. J Interv Card Electrophysiol. 2010;29(1):37–41.
  8. Jongnarangsin K, Chugh A, Good E, et al. Body mass index, obstructive sleep apnea, and outcomes of catheter ablation of atrial fibrillation. J Cardiovasc Electrophysiol. 2008; 19(7):668-672.